Dr. Damiano Rondelli, MD Professor of Medicine Director, Stem Cell Transplantation Program Contact Information Section of Hematology/Oncology, MC 734 University of Illinois at Chicago 909 S. Wolcott, Room 3051 Chicago, IL 60612 Phone: (312) 996-6179 Fax: (312) 413-4131 Email: drond@uic.edu Clinic Hours Wednesdays, 12:00 PM – 4:00 PM Thursdays, 9:00 AM – 12:00 PM For appointments, please call (312) 355-1625 Special Interests Stem cell transplant, myeloproliferative neoplasms Biography Dr. Rondelli received his medical degree from the University of Bologna in Bologna, Italy and then completed his Residency and Fellowship in Hematology at the Institute of Hematology at the University of Bologna as well. He started his research on immunology of stem cell transplantation at the Fred Hutchinson Cancer Center in Seattle, WA. Before joining UIC, Dr. Rondelli served as an Assistant Professor at the Institute of Hematology and Medical Oncology at the University of Bologna. Research Interests Dr. Rondelli's lab research focuses on stem cell transplant immunology, with particular interest in in-vitro and in-vivo models of anti-CD34+ cell T cell alloreactivity. Dr. Rondelli is actively involved in clinical research and is the Principal Investigator of investigator-inititiated Phase I and Phase II studies of allogeneic stem transplant for patients with high risk leukemia, lymphoma or myeloma, or for advanced myelofibrosis, or sickle cell anemia. Selected Publications 1. Rondelli D, Andrews RG, Hansen JA, Ryncarz R, Faerber MA, Anasetti C. Alloantigen presenting function of normal human CD34+ hematopoietic cells. Blood 88:2619-2625, 1996 PMID: 8839855. 2. Rondelli D, Lemoli RM, Ratta M, Fogli M, Re F, Curti A, Arpinati M, Tura S. Rapid induction of CD40 on a subset of G-CSF mobilized CD34+ blood cells identifies myeloid committed progenitors and permits selection of non-immunogenic CD40- progenitor cells. Blood 1999 94: 2293-2300. 3. Arpinati M, Chirumbolo G, Urbini B, Bonifazi F, Bandini G, Saunthararajah Y, Zagnoli A, Stanzani M, Falcioni S, Perrone G, Tura S, Baccarani M, Rondelli D. Acute GVHD and Steroid Treatment Impair Myeloid and Plasmacytoid Dendritic Cell Reconstitution after Allogeneic PBSC Transplantation. Biol Bone Marrow Transplant 2004: 10: 106-115. 4. Rondelli D, Barosi G, Bacigalupo A, Prchal JT, Popat U, Alessandrino EP, Spivak JL, Smith BD, Klingemann HG, Fruchtman S, Hoffman R. Allogeneic peripheral blood stem cell transplantation with reduced intensity conditioning in intermediate/high risk myelofibrosis patients. Blood 2005: 105:4115-9. 5. Abbasian J, Mahmud D, Mahmud N, Chunduri S, Araki H, Reddy P, Hoffman R, Arpinati M, Ferrara JL, Rondelli D. Allogeneic T cells induce rapid CD34+ differentiation into CD11c+CD86+ cells with direct and indirect antigen-presenting function. Blood 2006: 108: 203-208. 6. Chunduri S, Dobogai LC, Peace D, Saunthararajah Y, Quigley J, Chen YH, Mahmud N, Hurter E, Beri R, Rondelli D. Fludarabine/i.v. BU conditioning regimen: myeloablative, reduced intensity or both? Bone Marrow Transplant. 2008;41:935-40, 7. Arpinati M, Chirumbolo G, Marzocchi G, Baccarani M, Rondelli D. Increased Donor CD86+CD14+ cells in the Bone Marrow and Peripheral Blood of Patients with Chronic Graft-versus-Host Disease. Transplantation. 2008; 85:1826-32. 8. Beri R, Chunduri S, Sweiss K, Peace DJ, Mactal-Haaf C, Dobogai LC, Shord S, Quigley JG, Chen YH, Mahmud N, Rondelli D. Reliability of a pretransplant i.v. BU test dose performed 2 weeks before myeloablative FluBu conditioning regimen. Bone Marrow Transplant 2010: 45:249-53. 9. Mahmud D, Nicolini B, van den Dries L, Mahmud N, Rondelli D. Human CD4+CD25+ cells in combination with CD34+ cells and anti-thymocyte globulin to prevent anti-hematopoietic stem cell T cell alloreactivity. Biol Blood Marrow Transplant. 2011;17:61-8. 10. Varricchio L, Masselli E, Alfani E, Battistini A, Migliaccio G, Vannucchi AM, Zhang W, Rondelli D, Godbold J, Ghinassi B, Whitsett C, Hoffman H and Migliaccio AR. The dominant negative beta isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from patients with polycythemia vera. Blood. 2011;118:425-36.